Thing to consider must be presented to the discontinuation of promethazine HCl also to the use of other medicine if these reactions take place. Respiratory melancholy, nightmares, delirium, and agitated actions have also been claimed in some of these patients.

Promethazine with Codeine Oral Resolution needs to be used with caution in patients with bone-marrow melancholy. Leukopenia and agranulocytosis have been described, typically when promethazine has been Utilized in Affiliation with other recognized marrow-poisonous brokers.

Stimulation could be obvious, especially in young children and geriatric people. Convulsions may hardly ever manifest. A paradoxical reaction has been noted in little ones acquiring single doses of seventy five mg to a hundred twenty five mg orally, characterised by hyperexcitability and nightmares.

Notify individuals that a family teaspoon is not really an correct measuring product and this kind of use could lead on to overdosage and serious adverse reactions [see OVERDOSAGE (ten)]. For prescriptions exactly where a measuring gadget just isn't furnished, a pharmacist can provide an proper calibrated measuring unit and can offer Directions for measuring the proper dose.

In determining to employ a drugs, the threats of getting the drugs should be weighed in opposition to The nice it can do. This is often a call both you and your health care provider is likely to make. For this medication, the next must be regarded:

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Generally speak to your healthcare provider to make sure the information exhibited on this page relates to your personal conditions.

The dose of the medication will likely be diverse for various patients. Abide by your doctor's orders or maybe the directions on the label. The subsequent info contains only the common doses of this medicine. In the event your dose differs, do not modify it Until your doctor informs you to take action.

Promethazine with Codeine Oral Alternative is not really encouraged for use in pregnant Women of all ages [see Use in Distinct Populations (8.one)]. Prolonged use of Promethazine with Codeine Oral Alternative for the duration of pregnancy can lead to neonatal opioid withdrawal syndrome, which can be lifetime-threatening if not recognized and dealt with, and calls for management according to protocols made by neonatology authorities.

It's hard to website figure out what constitutes a typical toxic or lethal dose. Nevertheless, the lethal oral dose of codeine in an Grownup is claimed being during the choice of 0.

Cardiovascular: Keep an eye on for indications of hypotension, specifically in Those people whose blood pressure level is compromised

Snooze apnea, record of—Promethazine really should not be Employed in individuals with any of those conditions .

Lengthy-phrase animal experiments have not been done to evaluate the carcinogenic possible of codeine or of promethazine, nor are there other animal or human facts concerning carcinogenicity, mutagenicity, or impairment of fertility with these brokers.

Ensure you know how to consider this merchandise and what other prescription drugs you need to stay away from getting with it. See also Drug Interactions portion. Get healthcare support without delay if any of such very severe Negative effects come about: sluggish/shallow respiration, strange lightheadedness, critical drowsiness/dizziness, issue waking up.